A friend with an early MQ SWB had a few things tapped on the 1st battery and used to swap the batteries around every few months to 'keep wear even'. He said it was a pain, as the batteries are a little bit too heavy to be regularly swapping (risk of spilling corrosive substances on yourself, bodywork, wiring, etc in addition to strain injuries).
Due to the 'slow' nature of regulators, even for a small amplifier, I would recommend doubling the rating, for as a percentage swing, the reaction is less to allow the current flow at a given voltage - as suggested at least as big as the total of fuse values. If you are serious, put a local capacitor next to your amplifier. This provides extra current as a local reservoir to reduce clipping due to voltage drop under load.
I used to build competition car sound systems (if it doesn't at least have twin 12" subs it isn't a real stereo!), - not good when the sound system in your car is worth about double the vehicle it is mounted in... ($1800 head unit, $800 stacker, etc, etc, etc,) The last truck (Datsun 720 4x4 crew cab SD25) only had a SSB-CB (AM/FM dead, took out and threw away!), the SWB had the radio removed before I bought it and the LWB has some dodgey PoS that has a 24V regulator built in... So I haven't had a 'car radio' since before I got into 4x4's.
In light of what I'm reading from people's posts, either "Convert to 12V" or "Use voltage regulators".